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Project Information

CHARACTERIZING THE ROLE OF TRANSCRIPTIONAL REPRESSION IN MAIZE DEVELOPMENT AND DOMESTICATION

Agency:
NSF

National Science Foundation

Project Number:
1456950
Contact PI / Project Leader:
GALLAVOTTI, ANDREA
Awardee Organization:
RUTGERS THE ST UNIV OF NJ NEW BRUNSWICK

Description

Abstract Text:
Most of the world's food supply is provided either directly or indirectly by a few cultivated cereal species. Cereals generate their main edible product, grains, through a reproductive process that takes place in specialized structures called spikelets, which eventually give rise to flowers. Spikelet formation is carefully regulated by a network of genes that function at specific times during development. This is achieved through precise control of gene activity, either by activating or repressing mechanisms. The maize REL2 protein is essential for repressing gene activity in many developmental processes, among which are those that regulate the formation of spikelets and flowers. In this proposal the role of REL2 and REL2-like proteins are investigated in the development of maize, an economically important crop species. Overall, this research will reveal the molecular mechanisms controlling spikelet and flower formation, and will have far-reaching ramifications for both basic and applied plant research in maize and other agronomically valuable species. This project will impact undergraduate students and a post-doctoral researcher, providing them with a broad range of genetic, developmental, and genomic skills. High-school students and teachers will also be trained and exposed to the importance of protein interaction networks in biological systems.

The proposed research integrates genetic, molecular and genomic approaches to dissect the role of REL2-mediated transcriptional repression during maize development and will ultimately lead to: i) the functional characterization of the REL2 corepressor gene family; ii) the development of an integrated model for spikelet and flower formation; iii) a mechanistic understanding of a key step in the domestication of maize spikelets; and iv) the discovery of new proteins mediating transcriptional repression in different developmental pathways.
Project Terms:
biological systems; Cereals; Development; developmental genetics; Developmental Process; Flowers; Food Supply; Gene Family; gene function; gene repression; Genes; Genomic approach; Genomics; High School Student; Lead; Maize; Mediating; Modeling; Molecular; Molecular Genetics; Pathway interactions; Plants; Postdoctoral Fellow; Proteins; Reproductive Process; Research; Research Personnel; Role; skills; Structure; teacher; Time; Training; undergraduate student

Details

Contact PI / Project Leader Information:
Name:  GALLAVOTTI, ANDREA
Other PI Information:
Not Applicable
Awardee Organization:
Name:  RUTGERS THE ST UNIV OF NJ NEW BRUNSWICK
City:  NEW BRUNSWICK    
Country:  UNITED STATES
Congressional District:
State Code:  NJ
District:  06
Other Information:
Fiscal Year: 2015
Award Notice Date: 20-Jul-2015
DUNS Number: 001912864
Project Start Date: 01-Aug-2015
Budget Start Date:
CFDA Code: 47.074
Project End Date: 31-Jul-2020
Budget End Date:
Agency: ?

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National Science Foundation
Project Funding Information for 2015:
Year Agency

Agency: The entity responsible for the administering of a research grant, project, or contract. This may represent a federal department, agency, or sub-agency (institute or center). Details on agencies in Federal RePORTER can be found in the FAQ page.

FY Total Cost
2015 NSF

National Science Foundation

$776,000

Results

i

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