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Project Information

ORGANIZATIONAL INTERVENTIONS FOR SSI PREVENTION IN PEDIATRIC SPINAL SURGERY

Agency:
AHRQ

HHS/Agency for Healthcare Research and Quality

Project Number:
1K99HS022198-01
Contact PI / Project Leader:
MCLEOD, LISA M.
Awardee Organization:
UNIVERSITY OF COLORADO DENVER

Description

Abstract Text:
DESCRIPTION (provided by applicant): Dr. McLeod, MD, MSCE is a junior investigator in pediatric hospital medicine with advanced training in clinical epidemiology and quantitative analyses. Her research is focused on the comparative effectiveness of interventions for preventing surgical site infections (SSI) following spinal fusion operations in children, with an emphasis on the association between elements of the organizational contexts of care and patient-centered outcomes. In the K99 portion of this proposal, Dr. McLeod describes a multi-disciplinary career development program that will build on her existing skills and will provide advanced training in qualitative and mixed method research, quasi-experimental study designs, and implementation science, all of which will be instrumental to her future success as an independent health services investigator focused on the improvement of patient- centered outcomes in children hospitalized with complex medical and surgical conditions. The K99 research plan outlined in Aim 1 will use quantitative and qualitative methods to explore hospital-specific organizational factors that distinguish high versus low performance in SSI prevention (as determined by adjusted rates of SSI). In addition to providing Dr. McLeod with mentorship and rigorous training in mixed method research, completion of this project will generate hypotheses about organizational barriers and facilitators to the effective implementation of SSI prevention practices. These findings will then serve as the foundation for the R00 proposal (Aim 2) to independently execute a multi-center trial comparing the effectiveness of existing implementation strategies at low performing hospitals to the effectiveness of a tailored (informed by Aim1 barriers/facilitators), multi-disciplinary approach to designing, implementing, and evaluating a patient-focused and patient-informed intervention to reduce SSIs and the preventable harms resulting from them. Applying the skills and training acquired during the K99 phase, this trial will use a novel mixed method approach that addresses limitations in prior research by (1) allowing for the exploration of contextual factors that are not readily measured using quantitative methods alone, and (2) involving at all stages family perspectives on barriers and facilitators to improving quality and outcomes of care for their children. To accomplish her transition, Dr. McLeod has assembled an outstanding team of mentors led by Ron Keren, MD, MPH and renowned orthopedic surgeon, John Dormans, MD, and will continue to benefit from the rich resources offered by the University of Pennsylvania and Children's Hospital of Philadelphia. Importantly, this research will serve as a proof-of-concept for the use of comprehensive patient-focused strategies for improving the implementation effectiveness of interventions to prevent complications following surgical procedures in children, and will inform future multi-center trials to operationalize and test these strategies at other hospitals and for other conditions.
Project Terms:
Address; career development; Caring; Child; Childhood; clinical epidemiology; comparative effectiveness; compare effectiveness; Complex; contextual factors; design; Effectiveness; Effectiveness of Interventions; Elements; Family; Foundations; Future; Health Services; Hospitalized Child; Hospitals; implementation science; improved; Infection; Infection prevention; Intervention; Measures; Medical; Medicine; Mentors; Mentorship; Methods; novel; operation; Operative Surgical Procedures; Orthopedics; Outcome; Patient-Focused Outcomes; Patients; Pediatric Hospitals; Pennsylvania; Performance; Phase; Philadelphia; prevent; programs; Qualitative Methods; Research; Research Design; Research Methodology; Research Personnel; research study; Resources; Site; skills; skills training; Spinal; Spinal Fusion; Staging; success; Surgeon; Testing; Training; trial comparing; Universities

Details

Contact PI / Project Leader Information:
Name:  MCLEOD, LISA M.
Other PI Information:
Not Applicable
Awardee Organization:
Name:  UNIVERSITY OF COLORADO DENVER
City:  AURORA    
Country:  UNITED STATES
Congressional District:
State Code:  CO
District:  06
Other Information:
Fiscal Year: 2013
Award Notice Date: 15-May-2013
DUNS Number: 041096314
Project Start Date: 15-May-2013
Budget Start Date: 15-May-2013
CFDA Code: 226
Project End Date: 30-Apr-2015
Budget End Date: 30-Apr-2014
Agency: ?

Agency: The entity responsible for the administering of a research grant, project, or contract. This may represent a federal department, agency, or sub-agency (institute or center). Details on agencies in Federal RePORTER can be found in the FAQ page.

HHS/Agency for Healthcare Research and Quality
Project Funding Information for 2013:
Year Agency

Agency: The entity responsible for the administering of a research grant, project, or contract. This may represent a federal department, agency, or sub-agency (institute or center). Details on agencies in Federal RePORTER can be found in the FAQ page.

FY Total Cost
2013 AHRQ

HHS/Agency for Healthcare Research and Quality

$148,982

Results

i

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