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Project Information

RCN-UBE INCUBATOR: PREPARING A NETWORK TO DEVELOP MOLECULAR CASE STUDIES AT THE INTERFACE OF BIOLOGY AND CHEMISTRY

Agency:
NSF

National Science Foundation

Project Number:
1827011
Contact PI / Project Leader:
DUTTA, SHUCHISMITA
Awardee Organization:
RUTGERS THE ST UNIV OF NJ NEW BRUNSWICK

Description

Abstract Text:
Understanding structure-function relationships is foundational to learning biology. In lower-division courses, students study the shapes and functions of selected proteins and nucleic acids. However, deep understanding of structure-function relationships requires visualizing the structure, mapping information from various biological data resources (e.g., polymer sequence, interactions, mutations, variations) onto the structure, and applying biology and/or chemistry knowledge to synthesize explanations of function. Unfortunately, these activities are not common in undergraduate biology curricula. Collaboration between biology, chemistry, and biochemistry educators to adapt molecular visualization approaches currently being used in chemistry can benefit biology education. To that end, the aim of this project is to establish a network of interested faculty that will create case studies, an effective active-learning technique, to teach the relationship between molecular structure and function. The cases will enable students to visualize and analyze challenging real-world problems in atomic detail and apply their biology and/or chemistry knowledge to develop solutions. These molecular visualizations will provide a platform for integrating knowledge from different sub-disciplines of biology, such as biochemistry, genetics, and cell biology to form the foundation for practicing interdisciplinary, team science across STEM disciplines.This RCN-UBE project will establish a new network, Molecular CaseNet, to develop case studies at the interface of biology and chemistry. Objectives of the incubator phase of this project are to 1) bring together an interdisciplinary team of seven scientists and researchers to develop an exemplar for case-study design and determine format requirements for future case studies; 2) create two model case studies focused on specific biological processes/events and discussed at a molecular level; and 3) present the cases in community workshops and professional society meetings to recruit new members to the network and gather feedback on usability, clarity, and relevance of the case studies. Piloting the newly developed case studies with selected student groups will shed light on the relevance of these case studies in learning biology, chemistry, and biochemistry. By using the planned case studies, students with varied levels of expertise and disciplinary training will have the opportunity to understand molecular structure-function relationships and practice the scientific process to address real-world problems. In turn, this practice will help prepare the next generation of workers in STEM fields to creatively apply interdisciplinary approaches to problem-solving.This project is being jointly funded by the Directorate for Biological Sciences, Division of Biological Infrastructure, and the Directorate for Education and Human Resources, Division of Undergraduate Education as part of their efforts to address the challenges posed in Vision and Change in Undergraduate Biology Education: A Call to Action (http://visionandchange/finalreport/).This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.
Project Terms:
Active Learning; Address; Award; Biochemistry; Biological; Biological Process; Biological Sciences; Biology; Case Study; Cellular biology; Chemistry; Collaborations; Communities; data resource; Discipline; Education; Educational Curriculum; Educational workshop; Evaluation; Event; Faculty; Feedback; Foundations; Funding; Future; Genetic; Human Resources; Imagery; Incubators; Infrastructure; interdisciplinary approach; interest; Knowledge; Learning; Light; meetings; member; Mission; Modeling; Molecular; Molecular Structure; Mutation; Names; next generation; Nucleic Acids; Phase; Polymers; Problem Solving; Process; Professional Organizations; Proteins; recruit; Research Design; Research Personnel; Science; Scientist; Shapes; STEM field; Structure; Structure-Activity Relationship; Students; Techniques; Training; undergraduate education; undergraduate student; usability; Variant; Vision

Details

Contact PI / Project Leader Information:
Name:  DUTTA, SHUCHISMITA
Other PI Information:
MARCEY, DAVID J; MARSTELLER, PATRICIA A; CORTES, KIMBERLY J; TERRELL, CASSIDY R
Awardee Organization:
Name:  RUTGERS THE ST UNIV OF NJ NEW BRUNSWICK
City:  PISCATAWAY    
Country:  UNITED STATES
Congressional District:
State Code:  NJ
District:  06
Other Information:
Fiscal Year: 2018
Award Notice Date: 16-Aug-2018
DUNS Number: 001912864
Project Start Date: 01-Oct-2018
Budget Start Date:
CFDA Code: 47.074
Project End Date: 30-Sep-2019
Budget End Date:
Agency: ?

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National Science Foundation
Project Funding Information for 2018:
Year Agency

Agency: The entity responsible for the administering of a research grant, project, or contract. This may represent a federal department, agency, or sub-agency (institute or center). Details on agencies in Federal RePORTER can be found in the FAQ page.

FY Total Cost
2018 NSF

National Science Foundation

$75,000

Results

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